Toxins passed on through generations
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TOXIC chemicals that poisoned your grandparents, or even great-grand- parents, may also affect your health, according to American researchers. A study done on rats showed the effects of certain toxic chemicals that had been passed on through four generations of males.
The finding suggests that toxins may play a role in inherited diseases now blamed on genetic mutations. 'It's a new way to think about disease,' said Michael Skinner, direc- tor of the Centre for Reproductive Biology at Washington State University in Pullman.
For their study, Skinner and colleagues had injected pregnant rats with vinclozolin, a fungicide commonly used in vineyards, and the pesticide methoxychlor. Male rat pups born to these mothers had a 20 per cent lower than normal sperm count, were less motile and had less fertile sperm. When these male offspring were mated with females that had not been exposed to the toxins, 90 per cent of the new male offspring had similar problems. The effects had held for four generations.
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